 |
| Dexamethasone Amazon |
According to a BBC report , experts in the United Kingdom say that they have evidence the the widely available steroid called dexamethasone can cut the risk of death by up to one third for severely ill patients on ventilators. For those on oxygen, it cut deaths by one fifth.
The study were announced Tuesday and according to the group of researchers they would publish them soon. The study is a large, strict test that randomly assigned 2,104 patients to get the drug and compared them with 4,321 patients getting only usual care.
Dexamethasone was administered either orally or through an IV. After 28 days, it had reduced deaths by 35% in patients who needed treatment with ventilators and by 20% in those only needing supplemental oxygen. It did not appear to help less ill patients.
Chief investigator Prof Peter Horby of the University of Oxford said: "This is an extremely welcome result. The survival benefit is clear and large in those patients who are sick enough to require oxygen treatment, so dexamethasone should now become standard of care in these patients. Dexamethasone is inexpensive, on the shelf, and can be used immediately to save lives worldwide."
Nick Cammack of Wellcome, a British charity that supports science research said "countless lives will be saved globally. Dexamethasone must now be rolled out and accessed by thousands of critically ill patients around the world. It is highly affordable, easy to make, can be scaled up quickly and only needs a small dosage."
Steroid drugs can lessen inflammation, coronavirus patients sometimes suffers from inflammation as the immune system overreacts to fight the infection. This overreaction can prove fatal, so doctors have been testing steroids and other anti-inflammatory drugs in such patients. The World Health Organization advises against using steroids earlier in the course of illness because they can slow the time until patients clear the virus.
Researchers estimated that the drug would prevent one death for every eight patients treated while on breathing machines and one for every 25 patients on extra oxygen alone.
Also in the study, it said that the malaria drug hydroxychloroquine promoted by US president Donald Trump was ineffective against the coronavirus. The study enrolled more than 11,000 patients in England, Scotland, Wales and Northern Ireland who were given either standard of care or that plus one of several treatments: dexamethasone; the HIV combo drug lopinavir-ritonavir, the antibiotic azithromycin; the anti-inflammatory drug tocilizumab; or plasma from people who have recovered from COVID-19 that contains antibodies to fight the virus.
WellGrove Super Immunity Olive Leaf Extract Capsules $14.99
VitaRaw Immune Support Vitamins - Zinc, Elderberry, Vitamin C, Echinacea, Olive Leaf, Goldenseal $17.99
The NIHR-supported RECOVERY trial has shown that dexamethasone, a steroid, significantly reduces the risk of dying from #COVID19 for seriously ill patients requiring respiratory intervention - a major breakthrough https://t.co/KITpXiUcMr#priorityCOVIDresearch pic.twitter.com/W1ifVSPqDM— NIHR Research (@NIHRresearch) June 16, 2020
No comments:
Post a Comment